End Stage Kidney Disease, commonly known as renal failure, is a major threat to the global human health and medical insurance system. One tenth of the world ’s population will unfortunately suffer from chronic kidney disease at some stage of life, and the consequences may be catastrophic. According to statistics from the World Health Organization (WHO), currently, 2.4 million patients with renal failure worldwide will receive kidney dialysis equipment for their entire life unless they receive a transplant from a kidney donor. Patients with renal failure who have to be dialyzed every 4 hours on average consume a lot of energy and money.
The European Union's seventh research and development framework plan (FP7) information and communication technology (ICT) theme provides partial funding. The European NEPHRON + R & D team is composed of the participation of the scientific and technological circles and industrial circles of several EU member states. Using the scientific and technological achievements with independent intellectual property rights developed in the early stage, a wearable artificial kidney dialysis device was successfully developed. It is like a small school bag with a size of 40X20X4cm (cm), which can be conveniently carried on the body for continuous renal dialysis for 24 hours / 7 days. The working principle is the same as the traditional kidney dialysis equipment. On the premise of ensuring that the patient's blood pressure is at a safe level, the patient's blood is drawn through the filtering device to eliminate waste toxins. But compared with the traditional kidney dialysis equipment, the volume has been reduced by nearly a hundred times. Its main advantages are: 1) Portable and lighter, eliminating the trouble of patients going to and from the hospital dialysis center, and does not affect normal work and life; Body toxins, which are much better than traditional intermittent renal dialysis, can improve the life expectancy of patients on the original basis for 10-16 years, and can also prevent the "post-dialysis syndrome" that many patients often encounter; 3) Medical expenses The cost is lower, each patient can save at least 15-20 thousand euros in medical expenses per year, and the EU 340,000 kidney dialysis patients can save 5-7 billion euros in medical expenses each year, which does not include the patients who can work normally The value of; 4) Patients can monitor renal function data at any time to improve lifestyle, and maintain interaction with professional doctors through wireless connection.
At present, the NEPHRON R & D team is conducting rigorous clinical experiments on portable renal dialysis devices, but commercial partners have begun the production and sales arrangements for the device in the early stage. The technical and economic feasibility study report predicts that the annual market value of portable renal dialysis devices can reach 15 billion euros.
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