â— Provide basic nutrients: amino acids, vitamins, inorganic substances, lipids, nucleic acid derivatives, etc., which are essential for cell growth.
â— Provide hormones and various growth factors: insulin, adrenocortical hormone (hydrocortisone, dexamethasone), steroid hormones (estradiol, testosterone, progesterone). Growth factors such as fibroblast growth factor, epidermal growth factor, platelet growth factor and the like.
• Providing a binding protein: The binding protein acts to carry important low molecular weight substances, such as albumin carrying vitamins, fats, and hormones, and transferrin carries iron. Binding proteins play an important role in cellular metabolism.
• Provides pro-contact and stretching factors to protect cells from mechanical damage.
â— Some protection for cells in culture: Some cells, such as endothelial cells and bone marrow-like cells, can release proteases, and the serum contains anti-protease components to neutralize. This effect was discovered by chance, and now there is a purpose to use serum to stop the digestion of trypsin. Because trypsin has been widely used for digestion and passage of adherent cells. Serum proteins form a serum viscosity that protects cells from mechanical damage, especially when suspended in suspension. Serum also contains trace elements and ions, which play an important role in metabolic detoxification, such as SeO3, selenium, etc.
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